Which marker is a T-cell receptor profile marker among the listed options?

Which marker is a T-cell receptor profile marker among the listed options?

• A. CD3
• B. CD20
• C. TCR (alpha/beta)
• D. CD56

Answer: (C)

The main idea is identifying the marker that corresponds to the T-cell receptor itself. TCR alpha/beta is the receptor profile on most T cells, so it directly indicates the T-cell receptor type being expressed. CD3 marks T cells in general as part of the TCR signaling complex, but it isn’t the receptor type itself. CD20 is a B-cell marker, and CD56 is an NK cell marker. Therefore, the TCR (alpha/beta) is the best choice for a T-cell receptor profile marker.

The main idea is identifying the marker that corresponds to the T-cell receptor itself. TCR alpha/beta is the receptor profile on most T cells, so it directly indicates the T-cell receptor type being expressed. CD3 marks T cells in general as part of the TCR signaling complex, but it isn’t the receptor type itself. CD20 is a B-cell marker, and CD56 is an NK cell marker. Therefore, the TCR (alpha/beta) is the best choice for a T-cell receptor profile marker.